zo 1 (Proteintech)
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Proteintech
zo 1
Zo 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 97/100, based on 2559 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+zo-1/ZO-1+Antibody/pmc13650023-29-30-32
Average 97 stars, based on 2559 article reviews
Zo 1, supplied by Proteintech, used in various techniques. Bioz Stars score: 97/100, based on 2559 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+zo-1/ZO-1+Antibody/pmc13650023-29-30-32
Average 97 stars, based on 2559 article reviews
zo 1 - by Bioz Stars,
2026-10
97/100 stars
Images
1) Product Images from "Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD"
Article Title: Alkylating Agent–Induced FANCL Impairment Damages Pulmonary Arterial, Venous, and Microvascular Endothelial Cells and Predisposes to PAH/PVOD
Journal: Advanced Science
doi: 10.1002/advs.78081
Figure Legend Snippet: Effects of MMC and CDDP on Barrier Junction, Proliferation, and Tube Formation in Primarily Cultured Rat PAECs, PVECs, and PMVECs. (A, B) Immunofluorescence staining and quantification of ZO‑1 expression in PAECs, PVECs, and PMVECs treated with MMC (0.5 µg/mL) or CDDP (12 µM) for 24 or 48 h. n = 7 independent experiments for PAECs and n = 10 for PVECs and PMVECs. (C, D) Edu incorporation and quantification in PAECs, PVECs and PMVECs treated with MMC (0.5 µg/mL) or CDDP (12 µM) for 24 or 48 h. n = 5 independent experiments per group. (E, F) Tube formation images and quantification of the angiogenic capacity in PAECs, PVECs, and PMVECs treated with MMC (0.5 µg/mL) or CDDP (12 µM) for 24 or 48 h. n = 6 independent experiments per group. Data are presented as mean ± SD. Differences for B (ZO‐1 signal intensity) and D (EdU‐positive cell percentage) were analyzed by one‐way ANOVA with Tukey's HSD post hoc test. Differences between two groups in F were analyzed by unpaired t ‐test, except for the comparison of total segment length between Veh‐ and MMC‐treated PMVECs, for which the Mann–Whitney U‐test was used. A value of P < 0.05 is considered statistically significant, n.s. indicates no statistical significance. Scale bar = 50 µm in A and C, and 100 µm in E. Veh: vehicle control.
Techniques Used: Cell Culture, Immunofluorescence, Staining, Expressing, EdU Assay, Comparison, MANN-WHITNEY, Control
Figure Legend Snippet: Effects of MMC and CDDP on Functional Marker Protein Expression in Primary Cultured Rat PAECs, PVECs, and PMVECs. (A–L) Immunoblots and analyzed graphs showing the protein expression of ZO‐1, VEGFR2, FANCL, PCNA, Slug, Bcl2, Bax, and γ‐H2AX in PAECs, PVECs, and PMVECs treated with MMC (0.5 µg/mL) or CDDP (12 µM) for 24 or 48 h. Data are presented as mean ± SD, n = 5 rats per group. Data are presented as mean ± SD. Differences between two groups were analyzed by unpaired t ‐test, except for D (ZO1 at 48 h and VEGFR2 at 24 and 48 h), F (Bax/Bcl2 and γ‐H2AX at 24 h and Slug at 48 h), H (ZO1 at 24 h and PCNA at 48 h), and J (γ‐H2AX at 24 h), for which the Mann–Whitney U‐test was used. A value of P < 0.05 is considered statistically significant, n.s. indicates no statistical significance. (M, N) Heatmap of RNA‑seq data depicting gene‑ and pathway‑level changes in cultured rat PMVECs treated with MMC (0.5 µg/mL) or CDDP (12 µM) for 24 or 48 h. Veh: vehicle control.
Techniques Used: Functional Assay, Marker, Expressing, Cell Culture, Western Blot, MANN-WHITNEY, Control
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